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Immune cells found as accomplices in melanoma spread

31st January 2019

A new study published today in Cell has revealed that aggressive melanoma cells are able to manipulate the immune system to their advantage. As a result, immune cells that are supposed to recognise and destroy cancer cells actually behave differently and support the growth and spread of the tumour.

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‘The neighbouring effect’: Centrosomal abnormalities drive invasion of surrounding cells

19th November 2018

Centrosomal amplification, a particular change that occurs within some cancer cells, has been shown to drive the invasion of neighbouring cancer cells.

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New phase III clinical trial using combination therapy extends survival in triple-negative breast cancer

22nd October 2018

Research provides new hope for people with an aggressive type of breast cancer.

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Immunotherapy shows promise for patients with metastatic triple-negative breast cancer

17th October 2018

Immunotherapy has been shown to confer an encouraging survival benefit in patients with metastatic triple-negative breast cancer (mTNBC).

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Study links widely-used drug azathioprine to skin cancers

14th September 2018

A drug used to treat inflammatory bowel disease and arthritis, and prevent organ rejection in transplant patients, has been identified as an important contributor to skin cancer development in a study by researchers from Queen Mary University of London, including our Barts Cancer Research UK Centre (BCC) Bioinformatics team, the University of Dundee and the Wellcome Sanger Institute.

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‘Chromosomal Catastrophes’ in Colorectal Cancer

5th September 2018

Understanding how cancers develop and change over time is a big challenge. For obvious reasons, scientists can’t simply sit and watch a cancer growing in a person. Members of the Evolution and Cancer Laboratory at the BCI, including lead author Dr William Cross, were part of a collaborative team that set out to identify when particular genetic changes arise during bowel cancer development.

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