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PCRF’s national pancreas tissue bank opens to UK-based researchers
11th December 2020
The UK’s national tissue bank for pancreatic diseases at Barts Cancer Institute, Queen Mary University of London, is now open for UK-based researchers needing samples of blood, urine and saliva to aid their research.
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Understanding the role of the bone marrow in blood cell health and disease
3rd December 2020
Congratulations to Dr Miguel Ganuza from Barts Cancer Institute’s Centre for Haemato-Oncology who is the recipient of a Career Development Award from the Medical Research Council. The award of approximately £1.5 million over 5 years will fund a research project that will investigate how the bone marrow supports blood stem cells and how changes within the bone marrow can drive the development of diseases, such as leukaemia.
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Chromosomal instability in ovarian cancer
26th November 2020
We spoke with Dr Sarah McClelland and senior postdoctoral researcher in her group, Dr Nadeem Shaikh, about the team’s most recent paper, published in Cancer Research, which set out to explore the mechanisms of chromosomal instability in high-grade serous ovarian carcinoma – the most common type of ovarian cancer. The study sheds light on how these mechanisms may be able to be targeted to overcome treatment resistance in this cancer type.
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Our pancreatic cancer research
19th November 2020
November is Pancreatic Cancer Awareness Month and today (19th November) is World Pancreatic Cancer Day. Join us in looking back at some of our pancreatic cancer research from the last year.
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Protein powerhouses – Q&A with Dr Mardakheh
9th November 2020
We spoke with Dr Faraz Mardakheh from Barts Cancer Institute’s Centre for Cancer Cell and Molecular Biology about his most recent research paper, published today in Developmental Cell. The study sheds lights on how invasive cancer cells increase their protein-making capacity in order to boost their growth and invasive capabilities, and identifies a key player involved in this process, which may represent a target for therapeutic interventions.
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Protecting blood against premature ageing
9th November 2020
Researchers from Barts Cancer Institute, Queen Mary University of London, and the University of Edinburgh have discovered a key protein that supports the production of healthy blood cells throughout life by regulating the inflammatory response. This is the first study to identify a protein that directly keeps in check blood stem cells’ immune responses to protect them from excessive damage and premature ageing.
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