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Building a human tumour microenvironment in the lab

15th June 2021

Researchers from Barts Cancer Institute at Queen Mary University of London, led by Professor Fran Balkwill and Dr Oliver Pearce, have built two 3D multi-cellular models of the human tumour microenvironment (TME) in ovarian cancer. The models, which are the first created from the CanBuild project, have revealed novel insights into the role of the TME in cancer progression.

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Screening for ovarian cancer did not reduce deaths

13th May 2021

A large-scale randomised trial of annual screening for ovarian cancer did not succeed in reducing deaths from the disease, despite one of the screening methods tested detecting cancers earlier, according to results published in The Lancet.

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Impact of COVID-19 in patients with HBP conditions in East London

12th May 2021

Researchers from Barts Cancer Institute at Queen Mary University of London have conducted a population-based study to explore the risk factors associated with COVID-19 susceptibility and survival in patients with a history of diseases of the liver, pancreas or biliary system – also known as hepato-pancreato-biliary (HPB) diseases – in East London.

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Study to investigate how AI could aid early detection of pancreatic cancer

5th May 2021

Researchers from Barts Cancer Institute at Queen Mary University of London and Edge Hill University are set to investigate how artificial intelligence could be used to improve early diagnosis of pancreatic cancer.

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Long noncoding RNAs in genome stability and cancer

16th April 2021

Dr Lovorka Stojic, Group Leader in the Centre for Cancer Cell & Molecular Biology at Barts Cancer Institute, Queen Mary University of London, has recently received a Cancer Research UK Career Establishment Award to investigate the role of long noncoding RNAs in the maintenance of genome stability and in cancer.

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Impact of chemotherapy on immune cells in the TME

10th April 2021

Research from Barts Cancer Institute, Queen Mary University of London, has revealed novel insights into the effects of chemotherapy on the tumour microenvironment (TME). The study found that chemotherapy enhances the anti-tumour actions of immune cells within the TME and their ability to support immune responses against cancer.

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