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Professor Nick Lemoine
Director, CRUK Barts Centre; Medical Director, NIHR Clinical Research Network; Professor of Molecular Oncology

I am the Director of Barts Cancer Institute. My groups’ primary research interests are in the genomics and molecular pathology of pancreatic cancer and the development of oncolytic virotherapy.

Professor Kairbaan Hodivala-Dilke
Deputy Institute Director, Professor of the Tumour Microenvironment

Cancers are composed of both tumour and stromal compartments. We are interested in understanding the molecular basis of how the tumour stroma contributes to tumour growth, therapy resistance and spread, in various solid tumours including lung cancers, pancreatic cancer and melanoma.

Professor Hemant Kocher
Professor of Liver and Pancreas Surgery

My clinical research interests include tissue banking, clinical trials, innovative surgical techniques, epidemiology, meta-analysis and patient care pathways. My translational research interests include pancreatic cancer stroma and tumour-stroma cross-talk including cell signalling, adhesion, metastasis and invasion.

Professor John F. Marshall
Professor of Tumour Biology

I study the biology of tumour invasion with a particular focus on the roles of the adhesion molecules expressed on the cell surface that mediate this process. Our group concentrates on the study of integrins that are the principal family of adhesion molecules that mediate the interaction between cells and the extracellular matrix.

Mr Satyajit Bhattacharya
Honorary Reader

I am a clinical collaborator in numerous laboratory-based studies particularly the localisation of Lipiodol in Hepatocellular carcinomas, inflammatory and immune responses to surgery, and tumour-stroma interactions in pancreatic carcinoma. Clinical areas of interest have been video consultations in tertiary care, surgery for pancreatic tumours (especially NETs) and liver tumours, and tissue banking.

Dr Angus James Cameron
Senior Lecturer

My research focuses on kinases regulating cancer cell growth and motility to understand how and when to target them with drugs. My group is currently examining the role of the PKN kinases in malignant progression.

Professor Claude Chelala
Co-Director, Centre for Computational Biology, LSI; Professor of Bioinformatics

My research interests lie in the area of translational bioinformatics. Current research projects are focused in high-throughput data analysis, integration with clinical data, databases and software development, particularly for pancreatic cancer and breast cancer.

Professor Tatjana Crnogorac-Jurcevic
Professor of Molecular Pathology and Biomarkers

My research focuses on molecular pathology of pancreatic cancer, in particular its development and progression. We are using this knowledge to develop biomarkers for early, non-invasive detection of this malignancy in urine specimens.

Dr Mirjana Efremova
Lecturer

We are interested in understanding the cellular and molecular mechanisms that promote cancer cell plasticity and adaptation of tumour cells in metastatic niches and under therapeutic pressure.

Dr Gunnel Halldén
Reader in Cancer Gene Therapy

The research in our team is focused on the development of novel treatment strategies to target prostate and pancreatic cancers using genetically modified viruses that target, replicate and kill cancer cells but leave normal cells unharmed.

Dr Stéphanie Kermorgant
Reader in Cellular Oncology

We study the role of growth factor receptor signalling and intracellular trafficking (movement inside cells) in tumour growth and metastasis in the view of improving cancer therapy.

Dr David Propper
Honorary Senior Lecturer; Consultant Medical Oncologist

My focus is on detailed translational trials in pancreatic cancer, with a focus on targeting the tumour microenvironment. Our aim is to define what perturbations occur in tumours of patients receiving trial drugs.

Professor Yaohe Wang
Professor of Cancer Cell and Gene Therapy

We work on cancer prevention and immunotherapy using tumour-targeted replicating oncolytic viruses, in particular focusing on replicating adenovirus and vaccinia virus.

Dr Renato Brito Baleeiro

The primary focus of my research is to establish a platform for a neo-antigens-based vaccine for triple-negative breast cancer and pancreatic cancer.

Dr Silvana Debernardi

My work focuses on the global analysis of miRNA in pancreatic cancer and developing miRNA biomarkers for early detection of this malignancy.

Dr Michelle Goulart

My research is focused in understanding the tumour-stroma interactions in pancreatic cancer and the identification of potential biomarkers.

Dr Peng Liu

I am interested in cancer prevention and immunotherapy using tumour-targeted replicating oncolytic viruses.

Dr Shinelle G. Menezes

My work focuses on the influence of PKN2 on the immune-microenvironment, and the invasion and metastasis of pancreatic ductal adenocarcinoma in vivo, using murine models.

Dr Kate Moore

My research is focused on understanding how integrins help cancer cells invade and metastasise, as well as how we can use integrins as biomarkers of disease and therapeutic targets.

Dr Maximilian Mossner

My research is focussed on the disturbed epigenomic landscape within pancreatic tumours.

In particular, I investigate the bi-directional epigenetic reprogramming between the tumour microenvironment and pancreatic cancer stem cells that leads to cooperative tumour outgrowth.

Emma Newport

I am working to produce a bank of pancreatic cancer organoids from KPC mice. We hope to use these to model PDAC in vivo and in vitro.

Dr Helen Ross-Adams

The aim of my work is to develop clinically-relevant biomarkers that could aid in earlier disease detection, predict treatment response, and inform clinical management of patients.

Dr Remi Samain

My research is focused on understanding the role of contractility in pancreatic cancer.

Dr Pengju Wang

My work focuses on cancer immunotherapy using oncolytic viruses (vaccinia virus and adenovirus) and engineered T cells. I will also be looking at the state of immune cells in the tumour microenvironment.