Dr Michael Rushton

Postdoctoral Researcher
Research Focus

The aim of my research is to use the reprogramming of primed embryonic stem cells (ESCs) from the embryo inner cell mass (ICM) to ground state ESCs as a tool for elucidating the mechanisms involved in the regulation of DNA demethylation.

Identification of these mechanisms not only has implications in understanding the pathways involved in epigenetic reprgramming in development, but also in cancer where global hypomethylation is a hallmark of tumourigenesis.

Supervisor:
Dr Gabriella Ficz