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KEYNOTE-522: Immune therapy for breast cancer

30th September 2019

Results of an interim analysis from the KEYNOTE-522 trial have shown a treatment combination of immunotherapy plus chemotherapy to improve response rates in patients with early triple-negative breast cancer. Prof Peter Schmid presented the results at the ESMO Congress 2019 in Barcelona, Spain.

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Antibody therapy in pancreatic cancer

31st July 2019

Scientists have found a way to target and knock out a single protein that they have discovered is widely involved in pancreatic cancer cell growth, survival and invasion. Called avb6, the protein is present on the surface of more than 80 per cent of pancreatic ductal adenocarcinoma – the most common form of pancreatic cancer – and is vital to increase the successful growth and spread of the tumour cells.

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New research funded by PCRF

19th July 2019

The Pancreatic Cancer Research Fund is supporting two new research projects at the Barts Cancer Institute, Queen Mary University of London. The projects, led by Professor Hemant Kocher and Dr Gunnel Halldén, will aim to identify ways to enhance the efficacy of treatments for pancreatic cancer, to ultimately help those affected by this devastating disease.

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2019 ASCO Annual Meeting

4th June 2019

Professor Peter Schmid, Lead of the Centre for Experimental Cancer Medicine at the Barts Cancer Institute, Queen Mary University of London, attended this year’s ASCO Annual Meeting and today presented updated survival data from the IMpassion130 trial.

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AR alterations in prostate cancer

16th May 2019

Recent findings from a study published in JAMA Oncology have identified genetic markers within blood samples which may indicate whether patients with prostate cancer will respond to hormonal therapies. The study may represent an important step forward for the development of more personalised treatments for advanced prostate cancer.

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Therapy for high-grade glioma

2nd April 2019

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients. The trial used a treatment combination of ADI-PEG20, pemetrexed and cisplatin, which showed encouraging efficacy in patients with recurrent high-grade gliomas (HGGs), a disease for which little progress has been made over the last few decades.

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