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CRUK City of London Centre
The CRUK Barts Centre is a key partner in the CRUK City of London Centre, a centre of excellence in cancer biotherapeutics.
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How cancer cells shapeshift to spread through the body
Researchers show how cancer cells rearrange their inner workings to squeeze between obstacles
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BCI inspires young science stars
We welcomed more than 20 promising students from schools around the capital into the BCI.
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Unexpected inhibitor of breast cancer invasion revealed
The findings could help us to distinguish who will benefit from treatment
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Video: Illuminating the city of cells inside cancer
A new technique produces stunning images of tumours that provide crucial insights into cancer
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Pancreatic cancer cells (PANC-1) were grown into three-dimensional spheroids in a biomimetic hydrogel matrix for 14 days, then stained with DAPI (nuclei, blue), phalloidin (cytoskeleton, magenta), KRT19 (cancer marker, green). Spheroids were imaged by confocal microscopy and pictures were merged to create the image on the right. Top and bottom spheroids were created with individual colour overlay in ImageJ. The team aim to use these 3D models to better the understanding of cancer mechanobiology. Image by Eleonora Peerani, former BCI PhD student.
