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CRUK City of London Centre
The CRUK Barts Centre is a key partner in the CRUK City of London Centre, a centre of excellence in cancer biotherapeutics.
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Welcoming Professor Francesca Ciccarelli to the BCI
Professor Francesca Ciccarelli joins as Centre Lead for Cancer Genomics & Computational Biology
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Ovarian cancer's protective barrier: how the tumour matrix teaches cells to disarm immune attack
The results suggest new strategies to overcome cancer’s defences
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Clinical trial shows tumour-starving drug improves survival of mesothelioma
An innovative therapy provides new hope to patients with malignant mesothelioma.
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Vitamin B5 could improve red blood cell production in people with myelodysplastic syndromes
Improved understanding of this rare blood cancer could unlock the treatments of the future.
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Pancreatic cancer cells (PANC-1) were grown into three-dimensional spheroids in a biomimetic hydrogel matrix for 14 days, then stained with DAPI (nuclei, blue), phalloidin (cytoskeleton, magenta), KRT19 (cancer marker, green). Spheroids were imaged by confocal microscopy and pictures were merged to create the image on the right. Top and bottom spheroids were created with individual colour overlay in ImageJ. The team aim to use these 3D models to better the understanding of cancer mechanobiology. Image by Eleonora Peerani, former BCI PhD student.
