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Professor Trevor Graham
Professor of Cancer Evolution

My lab measures the patterns of clonal evolution that define carcinogenesis and develops novel mathematical tools for analysis and prediction. By characterising tumour evolution, we aim to find better ways to determine prognosis and more effective ways to treat cancers.

Professor Tatjana Crnogorac-Jurcevic
Professor of Molecular Pathology and Biomarkers

My research focuses on molecular pathology of pancreatic cancer, in particular its development and progression. We are using this knowledge to develop biomarkers for early, non-invasive detection of this malignancy in urine specimens.

Dr Gabriella Ficz
Senior Lecturer

My group aims to discover the epigenetic changes taking place during cancer initiation and develop potential drugs that can prevent these changes which may be abnormal but reversible, before many damaging mutations occur.

Dr Michelle Lockley
Reader in Medical Oncology, Honorary Consultant

Our lab aims to improve treatments for women with ovarian cancer, particularly those that are resistant to chemotherapy. We are interested in developing therapies that can adapt to the evolution of chemotherapy resistance over time.

Dr Sarah McClelland
Senior Lecturer

My lab aims to understand the mechanisms that underlie numerical and structural chromosome aberrations in cancer at a molecular level, which also involves understanding how normal cells replicate and segregate their genomes.

Dr Lovorka Stojic
Lecturer

My group studies how RNA-mediated mechanisms, in particular long noncoding RNAs, regulate cell division and how dysregulation of these processes leads to genome instability and cancer.

Dr Jun Wang
Senior Lecturer

My main research interests lie in applying bioinformatics and computational approaches to analyse large-scale cancer datasets to uncover novel diagnostic and prognostic features. I also lead the CRUK Barts Centre Bioinformatics Core Facility.

Dr Benjamin Werner
Lecturer

My group combines mathematics, computer simulations and genomic information to study evolutionary processes. We aim to understand how a tumour’s evolutionary history is reflected in its genome, how evolution can be quantified in individual tumours and how this information predicts future evolution.

Dr Hannah Armes

The aim of my research project is to identify and functionally characterise candidate disease genes in familial leukaemia.

Dr Juliana Candido

My research project aims to study the role of the immune cell infiltration in the tumour microenvironment of pancreatic cancer.

Dr Kit Curtius
UKRI/Rutherford Research Fellow

The aims of my current research are to use mathematical mechanistic modelling to inform optimal cancer screening recommendations, to perform patient risk stratification, and to ultimately better prognostication.