Professor Trevor Graham
Professor of Cancer Evolution
My lab measures the patterns of clonal evolution that define carcinogenesis and develops novel mathematical tools for analysis and prediction. By characterising tumour evolution, we aim to find better ways to determine prognosis and more effective ways to treat cancers.
Professor Tatjana Crnogorac-Jurcevic
Professor of Molecular Pathology and Biomarkers
My research focuses on molecular pathology of pancreatic cancer, in particular its development and progression. We are using this knowledge to develop biomarkers for early, non-invasive detection of this malignancy in urine specimens.
Dr Gabriella Ficz
Senior Lecturer
My group aims to discover the epigenetic changes taking place during cancer initiation and develop potential drugs that can prevent these changes which may be abnormal but reversible, before many damaging mutations occur.
Dr Michelle Lockley
Reader in Medical Oncology, Honorary Consultant
Our lab aims to improve treatments for women with ovarian cancer, particularly those that are resistant to chemotherapy. We are interested in developing therapies that can adapt to the evolution of chemotherapy resistance over time.
Dr Sarah McClelland
Senior Lecturer
My lab aims to understand the mechanisms that underlie numerical and structural chromosome aberrations in cancer at a molecular level, which also involves understanding how normal cells replicate and segregate their genomes.
Dr Lovorka Stojic
Lecturer
My group studies how RNA-mediated mechanisms, in particular long noncoding RNAs, regulate cell division and how dysregulation of these processes leads to genome instability and cancer.
Dr Jun Wang
Senior Lecturer
My main research interests lie in applying bioinformatics and computational approaches to analyse large-scale cancer datasets to uncover novel diagnostic and prognostic features. I also lead the CRUK Barts Centre Bioinformatics Core Facility.
Dr Benjamin Werner
Lecturer
My group combines mathematics, computer simulations and genomic information to study evolutionary processes. We aim to understand how a tumour’s evolutionary history is reflected in its genome, how evolution can be quantified in individual tumours and how this information predicts future evolution.
Dr Hannah Armes
The aim of my research project is to identify and functionally characterise candidate disease genes in familial leukaemia.
Dr Jacob Househam
I am a computational biologist focussing on understanding the evolutionary dynamics that underpin colorectal cancer progression.