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Chromosomal instability in ovarian cancer
26th November 2020
We spoke with Dr Sarah McClelland and senior postdoctoral researcher in her group, Dr Nadeem Shaikh, about the team’s most recent paper, published in Cancer Research, which set out to explore the mechanisms of chromosomal instability in high-grade serous ovarian carcinoma – the most common type of ovarian cancer. The study sheds light on how these mechanisms may be able to be targeted to overcome treatment resistance in this cancer type.
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Immune ‘cloaking’ in cancer cells
14th September 2020
Researchers have created a mathematical model that can determine the impact of the immune system on tumour evolution. The information gained from using this model may be able to be used to predict whether immunotherapy is likely to be effective for a patient’s cancer, helping to guide treatment decisions.
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Using AI to study tumour evolution
2nd September 2020
Researchers have developed a computation model that can reconstruct the evolutionary history of cancer. By unravelling the genetic complexity of a tumour, the tool can be used to better understand how the cancer has developed and may help to guide treatment strategies in the future.
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International Women’s Day 2020
6th March 2020
In recognition of International Women’s Day on 8th March, we spoke to some of our female scientists about their roles and inspirations.
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New and valuable insights into familial myeloid leukaemia
3rd March 2020
Research has identified new genetic features implicated in a type of blood cancer known as familial myeloid leukaemia. The study, published in Nature Communications, offers novel insights into the biology of this inherited cancer, and provides a framework to inform how to more effectively manage at-risk individuals and patients affected by this type of blood malignancy.
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Prof Manchanda awarded prestigious oration
16th December 2019
Professor Ranjit Manchanda delivered the Shyam Agarwal Memorial Oration at the Indian Society of Cancer Genetics Conference on 15 December.
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