There are around 7,500 new ovarian cancer cases in the UK every year and more than half of those diagnosed will die of the disease. There is no screening technique, and most patients (~60%) present with advanced disease because symptoms are not easy to recognise or distinguish from other, less serious conditions, often leading to late or mis‑diagnosis. Treatment involves aggressive surgery and platinum-based chemotherapy, and progress in the last 30 years has led to the overall five year survival rate doubling and more than 40% of women now live for at least five years. However, for the majority who present with advanced disease, more than 70% will die within five years of diagnosis. Therefore, there is a great need to develop new therapies for this disease, based upon greater understanding of its biology.