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Professor Kairbaan Hodivala-Dilke
Deputy Institute Director, Professor of the Tumour Microenvironment

Cancers are composed of both tumour and stromal compartments. We are interested in understanding the molecular basis of how the tumour stroma contributes to tumour growth, therapy resistance and spread, in various solid tumours including lung cancers, pancreatic cancer and melanoma.

Dr Jesus Gomez Escudero

I am involved in some projects that are focused in the stroma components of a tumour, particularly the endothelial vessels, and its potential role in some key processes including chemotherapy or metastasis.

Emma Newport

I am working to produce a bank of pancreatic cancer organoids from KPC mice. We hope to use these to model PDAC in vivo and in vitro.

Dr Alexandra Njegic

My research focuses on how we can therapeutically target integrins to modulate angiogenesis in heart failure.

Dr Rita Pedrosa

My work will identify other players in the regulation of angiocrine signalling using a CRISPR screen. I will also explore the molecular mechanisms underlying how FAK controls angiocrine signalling.

Dr Laura Wisniewski

My project looks at the modelling of cancer for improved therapy development. I am carrying out in vivo cancer experiments, with and without modifications of the tumour microenvironment, to examine effects of such treatments on anti-cancer therapy efficacy.