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Professor Kairbaan Hodivala-Dilke
Deputy Institute Director, Professor of the Tumour Microenvironment

Cancers are composed of both tumour and stromal compartments. We are interested in understanding the molecular basis of how the tumour stroma contributes to tumour growth, therapy resistance and spread, in various solid tumours including lung cancers, pancreatic cancer and melanoma.

Dr Gabriela d’Amico Lago

My work is focused on understanding the roles of kinase and non-kinase motifs of FAK in controlling physiological angiogenesis in vivo. Overall my goal is to understand how to best control tumour blood vessels in the regulation of cancer.

Dr Jesus Gomez Escudero

I am involved in some projects that are focused in the stroma components of a tumour, particularly the endothelial vessels, and its potential role in some key processes including chemotherapy or metastasis.

Dr Jose Munoz-Felix

My main project is to use a CRIPSR screen to identify novel vascular promotion/chemosensitisation targets. Additionally, I am investigating the utility of this approach in the treatment of other fibrotic diseases.

Dr Rita Pedrosa

My work will identify other players in the regulation of angiocrine signalling using a CRISPR screen. I will also explore the molecular mechanisms underlying how FAK controls angiocrine signalling.