Dr Rita Pedrosa

Postdoctoral Researcher
Research Focus

Unpicking the molecular mechanisms underlying angiocrine signalling

Upon DNA-damaging therapy, blood vessels produce a cocktail of cytokines and chemokines – the angiocrine signal. Our laboratory recently published evidence that FAK can control this angiocrine signal and that this can help sensitise tumours to DNA-damaging therapy.

My work will identify other players in the regulation of angiocrine signalling using a CRISPR screen. I will also explore the molecular mechanisms underlying how FAK controls angiocrine signalling.

Professor Kairbaan Hodivala-Dilke