Tag: Genetics

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New tool predicts risk of skin cancer spread more accurately than human inspection

12th October 2023

These results could aid the treatment of individuals most at risk of aggressive skin cancer.

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BCI researchers part of international team shortlisted for Cancer Grand Challenges award

5th September 2023

Dr Özgen Deniz and Dr Benjamin Werner are part of a team shortlisted for these prestigious awards

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Understanding the role of cancer’s circular genome in tumour evolution

23rd September 2022

New research, co-led by Dr Benjamin Werner from Barts Cancer Institute at Queen Mary University of London, indicates that the circular DNA structures present in around a third of cancers lead to extensive genetic diversity within tumours, giving them the ability to adapt rapidly to environmental stress and resist targeted cancer treatment.

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BCI researcher receives new Pancreatic Cancer UK Fellowship

20th July 2022

Congratulations to Dr Audrey Lumeau, Postdoctoral Researcher at Barts Cancer Institute, Queen Mary University of London, who has received a Career Foundation Fellowship from the charity Pancreatic Cancer UK to investigate chromosomal instability in pancreatic cancer and its role in therapy resistance.

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£3.1 million for PROTECT trial

6th May 2022

Yorkshire Cancer Research has announced a £3.1 million grant for research led by Ranjit Manchanda to investigate the risks, benefits, and feasibility of introducing population-based genetic testing for ‘all’ women to find out if they are at high risk of cancer. Thousands of women living in Yorkshire and other parts of the UK will be offered tests as part of the PROTECT (Population based germline testing for early detection and cancer prevention) clinical trial.

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Turning back the molecular clock: Tracing cell lineage

6th January 2022

Researchers from Barts Cancer Institute at Queen Mary University of London, the Moffitt Cancer Center and the University of Southern California, have developed a new method that measures subtle changes to the genetic code of cells (called DNA methylation) to study the dynamics of what happens to cells within our bodies over time. The new method, published in Nature Biotechnology, provides a way to measure the birth and death of human cells, making it possible to trace cell lineage and evolution.

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