Tag: Invasion

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Protein powerhouses – Q&A with Dr Mardakheh

9th November 2020

We spoke with Dr Faraz Mardakheh from Barts Cancer Institute’s Centre for Cancer Cell and Molecular Biology about his most recent research paper, published today in Developmental Cell. The study sheds lights on how invasive cancer cells increase their protein-making capacity in order to boost their growth and invasive capabilities, and identifies a key player involved in this process, which may represent a target for therapeutic interventions.

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Aggressive melanoma cells at edge of tumours are key to cancer spread

20th October 2020

Research led by Barts Cancer Institute, Queen Mary University of London, has revealed novel insights into the mechanisms employed by melanoma cells to form tumours at secondary sites around the body. The findings from the study may help to identify new targets to inhibit melanoma spread and guide treatment decisions in the clinic.

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‘The neighbouring effect’: Centrosomal abnormalities drive invasion of surrounding cells

19th November 2018

Centrosomal amplification, a particular change that occurs within some cancer cells, has been shown to drive the invasion of neighbouring cancer cells.

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