Tag: Models

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Mouse models of ovarian cancer

27th January 2020

Research led by the Barts Cancer Institute, Queen Mary University of London, has revealed that mouse models of the most common and deadly form of ovarian cancer, high-grade serous ovarian cancer, can effectively replicate the disease in humans. These models provide useful pre-clinical tools that may help to determine which patients are likely to respond to particular treatments.

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First steps towards a vaccine for pancreatic cancer

26th November 2019

Researchers from Barts Cancer Institute and Zhengzhou University have developed a personalised vaccine system that could ultimately delay the onset of pancreatic cancer. The study reports the team’s work with a pre-clinical model using mice, and provides strong proof-of-concept for the creation of a vaccine for cancer prevention in individuals at high risk of developing this disease.

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Antibody therapy in pancreatic cancer

31st July 2019

Scientists have found a way to target and knock out a single protein that they have discovered is widely involved in pancreatic cancer cell growth, survival and invasion. Called avb6, the protein is present on the surface of more than 80 per cent of pancreatic ductal adenocarcinoma – the most common form of pancreatic cancer – and is vital to increase the successful growth and spread of the tumour cells.

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IBD and bowel cancer

29th April 2019

April is Bowel Cancer Awareness Month. We recently spoke with Dr Kit Curtius about her work which focuses on understanding how normal tissues evolve to become cancerous, with a particular interest in gastrointestinal pre-malignancies such as inflammatory bowel disease.

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Flying in the face of cancer

27th February 2019

Using flies to reveal mechanisms of cancer development- Q&A with Dr Ribeiro Dr Paulo Ribeiro and his team. From left to right: Paulo Ribeiro, Lauren Dawson, Alberto Rizzo and Damien Goutte-Gattat. Dr Paulo Ribeiro is a Senior Lecturer and Group Leader in our Centre for Tumour Biology. His research group focuses on uncovering the molecular mechanisms […]

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