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AR alterations in prostate cancer

16th May 2019

Recent findings from a study published in JAMA Oncology have identified genetic markers within blood samples which may indicate whether patients with prostate cancer will respond to hormonal therapies. The study may represent an important step forward for the development of more personalised treatments for advanced prostate cancer.

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Eliminating cancer stem cells

25th April 2019

Research published today in Cell Stem Cell has discovered a protein which drives an aggressive form of blood cancer, acute myeloid leukaemia (AML). Inactivation of this protein selectively compromises leukaemic cells while promoting normal blood cell functions.

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Therapy for high-grade glioma

2nd April 2019

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients. The trial used a treatment combination of ADI-PEG20, pemetrexed and cisplatin, which showed encouraging efficacy in patients with recurrent high-grade gliomas (HGGs), a disease for which little progress has been made over the last few decades.

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Flying in the face of cancer

27th February 2019

Using flies to reveal mechanisms of cancer development- Q&A with Dr Ribeiro Dr Paulo Ribeiro and his team. From left to right: Paulo Ribeiro, Lauren Dawson, Alberto Rizzo and Damien Goutte-Gattat. Dr Paulo Ribeiro is a Senior Lecturer and Group Leader in our Centre for Tumour Biology. His research group focuses on uncovering the molecular mechanisms […]

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Tackling tumour scar tissue could be key to treating pancreatic cancer

11th February 2019

The first study in the world to take a detailed look at scar tissue in human pancreatic cancer has revealed a range of different scar tissue types that could help clinicians predict which patients will respond best to particular treatments.

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Immune cells found as accomplices in melanoma spread

31st January 2019

A new study published today in Cell has revealed that aggressive melanoma cells are able to manipulate the immune system to their advantage. As a result, immune cells that are supposed to recognise and destroy cancer cells actually behave differently and support the growth and spread of the tumour.

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