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Professor Jude Fitzgibbon
Professor of Personalised Cancer Medicine

My research group works on molecular pathology, genetics and progression of leukaemia and lymphomas, aiming to improve on current diagnostic, prognostic and treatment strategies.

Dr Andrejs Braun
Senior Lecturer

I am interested in the mechanisms of tumour clearance in response to targeted therapy with monoclonal antibodies. I work on antibody therapies for lymphoma and the epigenetics of somatic hypermutation in normal and malignant B cells.

Dr Jeff Davies
Reader in Haemato-oncology and Honorary Consultant

My group works on developing novel approaches to improve efficacy and safety of allogeneic stem cell transplantation and adoptive immunotherapy as treatments for blood cancers. We focus on T-cell alloreactivity in the context of stem cell transplantation and immunotherapy.

Dr Paolo Gallipoli
Clinical Senior Lecturer in Haemato-Oncology

My research interests focus on mechanisms of disease initiation and maintenance and the identification and validation of novel therapeutic targets in myeloid leukaemias.

Professor John Gribben
Professor of Medical Oncology

My group focuses on immunological approaches to the treatment of haematological cancers. My primary research interests include the immunotherapy of cancer (including stem cell transplantation), the identification of B-cell-tumour antigens; and the detection and treatment of minimal residual disease in leukaemia and lymphoma.

Professor Kamil R. Kranc
Clinical Professor of Haematology

Our research aims to understand the biology of leukaemia stem cells and identify tricks they use to escape treatments. My group employs multidisciplinary approaches to understand how HSCs chose to self-renew or differentiate and how these cell fate decisions are affected under pathological conditions to generate leukaemic stem cells.

Dr Sergey Krysov
Senior Lecturer

My studies concentrate on the immunogenetics of human B cell malignancies, such as chronic lymphocytic leukaemia, follicular lymphoma and the role for B cell receptor in the development of B cell lymphoma and leukaemia.

Dr Rifca Le Dieu
Clinical Senior Lecturer

I am the Module Lead for 3 undergraduate Biomedical Science Modules. I am also the Cancer Theme Lead for MBBS with direct responsibility for Year 2 Cancer Week. In addition, I supervise MSc project dissertations.

Dr Jessica Okosun
Clinical Senior Lecturer

My research focuses on understanding the genetic and molecular mechanisms that underlie the initiation and progression of B-cell non-Hodgkin’s lymphomas in order to define clinically-relevant biomarkers.

Dr John Riches
Clinical Senior Lecturer

My major research interest is understanding the metabolism of chronic lymphocytic leukaemia and lymphoma with the aim that this will underpin the development of the next generation of anti-metabolic drugs for these diseases.

Dr Kevin Rouault-Pierre
Lecturer

My main research interests are in haematopoietic stem cells (HSCs) and leukemic initiating cells. I seek to understand how intrinsic and extrinsic signals are integrated by normal and malignant stem cells.

Dr Bela Wrench
Clinical Senior Lecturer

My research focuses on the fundamental aspects of leukaemia initiating cell (LIC) biology in adult acute lymphoblastic leukaemia, with the aim of gaining fundamental insight into the underlying biology of LICs to reveal dependencies that are tractable targets for therapy.

Dr Hannah Armes

The aim of my research project is to identify and functionally characterise candidate disease genes in familial leukaemia.

Dr Findlay Redvers Bewicke-Copley

My work is currently focused on lymphoma, working on variant calling and gene expression analysis of NGS data.

Dr David Britton

My project is focused on determining how certain proteins enable acute myeloid leukaemia blasts to acquire or have intrinsic resistance to chemotherapy, with the aim to identify suitable pharmaceutical alternatives to combat resistance.

Dr Juliana Candido

My research project aims to study the role of the immune cell infiltration in the tumour microenvironment of pancreatic cancer.

Dr Pedro Casado-Izquierdo

My work is based on studying signalling networks in AML primary samples in order to predict responses to kinase inhibitors.

Dr Marta Crespi-Sallan

My research is focused on describing the mechanisms underlying Lamin B1 nuclear disassembly in B-cell normal development and how a dis-regulated Lamin B1 removal pathway could lead to several haematological malignancies within the germinal centre in secondary lymph organs.

Dr Quentin Heydt

My research focuses on the fundamental aspects of leukaemia initiating cell biology in adult acute lymphoblastic leukaemia.

Dr Alice Mazzagatti

Our work aims to better understand aneuploidy tolerance in cancer, in particular with regard to monosomy in AML.

Dr Celine Philippe

My project focuses on the translation reprogramming in acute myeloid leukaemia upon stresses such as chemotherapy.

Dr Ana Rio-Machin

My research project aims to identify germline mutations in families with leukaemia of unknown aetiology and study the intra and inter leukaemia heterogeneity observed in these families, through examination of clonal evolution and secondary genetic events.

Dr Filomena Spada

My research involves using mass cytometry based analysis to characterise the interaction, activation, and signalling capacity of B and T-cells in CLL and other B-cell malignancies.

Dr Louie van de Lagemaat

I use computational biology techniques to understand how normal RNA regulatory mechanisms used in development are hijacked in cancers.

Dr Chrysi Xintaropoulou

The aim of my research is to elucidate the biology of leukaemia initiating cells, responsible for disease recurrence, in acute lymphoblastic leukaemia.