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Follicular lymphoma marked by spatial tumour heterogeneity

23rd March 2018

A research team at the BCI, Queen Mary University of London, led by Dr Jessica Okosun, Centre for Haemato-Oncology, has found that tumours at different sites within the same patient with follicular lymphoma can be genetically diverse. This suggests that a sole biopsy is incapable of capturing all the genetic events in any given individual and presents a significant challenge when providing targeted therapies to treat this disease.

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Seema Jaswal visits the BCI

15th March 2018

Last Thursday was International Women’s Day- a day that celebrates the social, political, cultural and economic achievements of women from all over the world. Recently, an inspirational woman, Seema Jaswal- a television and radio presenter- visited us here at the Barts Cancer Institute (BCI) to meet some of our researchers and find out more about the cutting edge research that goes on here.

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Dr Ranjit Manchanda awarded William Blair Bell Memorial Lecture

9th March 2018

Congratulations to our Dr Ranjit Manchanda, Centre for Experimental Cancer Medicine, who has been awarded the William Blair Bell Memorial Lecture prize. Dr Ranjit Manchanda was awarded with the prize on 8th February and presented his lecture, entitled ‘Population based germline testing and targeted ovarian cancer prevention,’ the following day.

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Switching on survival signalling to drive drug resistance

27th February 2018

Researchers at the Barts Cancer Institute (BCI), Queen Mary University of London, led by Dr Richard Grose, Centre for Tumour Biology, have discovered that the loss of a single protein- PHLDA1- is sufficient for the development of drug resistance to a type of targeted therapy in endometrial and HER2-positive breast cancer cells.

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The involvement of the microenvironment in tumour evolution

15th February 2018

For the first time, researchers at the Barts Cancer Institute (BCI), Queen Mary University of London, have profiled what happens at the site of tumour metastasis as cancer grows and develops. By looking closely at the tumour microenvironment (TME), the team led by Professor Fran Balkwill, Lead for the Centre for Cancer & Inflammation, has identified changes that occur as a type of ovarian cancer evolves.

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STORMing Cancer shortlisted for Cancer Research UK’s Grand Challenge Award

8th February 2018

STORMing Cancer, a team of multi-disciplinary scientists including our own Dr Stuart McDonald, from the Centre for Tumour Biology, has been shortlisted to the final stages of Cancer Research UK (CRUK)’s Grand Challenge Award- the world’s most ambitious cancer research grant consisting of a series of £20 million awards seeking researchers to tackle cancer’s toughest challenges. In their proposed […]

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