Tag: Viruses

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Using a modified adenovirus to overcome treatment resistance in prostate cancer

27th April 2018

Researchers from BCI’s Centre for Molecular Oncology, led by Dr Gunnel Halldén, have identified a mechanism by which a modified flu-like virus, called AdDD, is able to negate resistance to a drug called mitoxantrone and increase tumour cell killing in prostate cancer models. This mechanism is dependent on B-cell lymphoma 2 (Bcl-2)- a protein involved in the regulation of cell death (apoptosis).

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Researchers use flu-like virus to attack pancreatic cancer

25th January 2018

A flu-like virus has now been used in experiments to successfully inhibit the growth of pancreatic cancer, according to an early study by researchers at the Barts Cancer Institute (BCI) of Queen Mary University of London (QMUL).

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